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BioResource International Inc human malignant peripheral nerve sheath tumour cell line nms2
Differential diagnosis of synovial sarcoma from other soft tissue sarcomas by circulating/secreted miR-92b-3p . ( A , B ) The expression of miR-92b-3p and miR-150-3p in cells ( A ) and cell culture media ( B ) of SS (SYO-1, YaFuSS, HS-SY-II, and Yamato-SS) and the other STS cell lines (HT1080, <t>NMS2,</t> and UPS2023). The Mann-Whitney U test was used for comparison between groups. ( C ) Serum miR-92b-3p levels in SS patients and other STS patients ( p < 0.001). The Mann-Whitney U test was used for comparison between groups. ( D ) ROC curve analysis of miR-92b-3p discriminating SS patients from other STS patients. AUC was 0.88 (95% confidence interval = 0.72–1.0). ( E ) Serum miR-150-3p expression levels in SS patients and other STS patients. The Mann-Whitney U test was used for comparison between groups. ( F ) ROC curve analysis of miR-150-3p discriminating SS patients from other STS patients. AUC was 0.54 (95% confidence interval = 0.33–0.75).
Human Malignant Peripheral Nerve Sheath Tumour Cell Line Nms2, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Differential diagnosis of synovial sarcoma from other soft tissue sarcomas by circulating/secreted miR-92b-3p . ( A , B ) The expression of miR-92b-3p and miR-150-3p in cells ( A ) and cell culture media ( B ) of SS (SYO-1, YaFuSS, HS-SY-II, and Yamato-SS) and the other STS cell lines (HT1080, NMS2, and UPS2023). The Mann-Whitney U test was used for comparison between groups. ( C ) Serum miR-92b-3p levels in SS patients and other STS patients ( p < 0.001). The Mann-Whitney U test was used for comparison between groups. ( D ) ROC curve analysis of miR-92b-3p discriminating SS patients from other STS patients. AUC was 0.88 (95% confidence interval = 0.72–1.0). ( E ) Serum miR-150-3p expression levels in SS patients and other STS patients. The Mann-Whitney U test was used for comparison between groups. ( F ) ROC curve analysis of miR-150-3p discriminating SS patients from other STS patients. AUC was 0.54 (95% confidence interval = 0.33–0.75).

Journal: Scientific Reports

Article Title: Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma

doi: 10.1038/s41598-017-12660-5

Figure Lengend Snippet: Differential diagnosis of synovial sarcoma from other soft tissue sarcomas by circulating/secreted miR-92b-3p . ( A , B ) The expression of miR-92b-3p and miR-150-3p in cells ( A ) and cell culture media ( B ) of SS (SYO-1, YaFuSS, HS-SY-II, and Yamato-SS) and the other STS cell lines (HT1080, NMS2, and UPS2023). The Mann-Whitney U test was used for comparison between groups. ( C ) Serum miR-92b-3p levels in SS patients and other STS patients ( p < 0.001). The Mann-Whitney U test was used for comparison between groups. ( D ) ROC curve analysis of miR-92b-3p discriminating SS patients from other STS patients. AUC was 0.88 (95% confidence interval = 0.72–1.0). ( E ) Serum miR-150-3p expression levels in SS patients and other STS patients. The Mann-Whitney U test was used for comparison between groups. ( F ) ROC curve analysis of miR-150-3p discriminating SS patients from other STS patients. AUC was 0.54 (95% confidence interval = 0.33–0.75).

Article Snippet: A human malignant peripheral nerve sheath tumour cell line NMS2 was available from the cell bank of RIKEN BioResource Center (Ibaraki, Japan).

Techniques: Biomarker Discovery, Expressing, Cell Culture, MANN-WHITNEY, Comparison